产品货号：
Z14564
中文名称：
FLIP/CFLAR抗体
英文名称：
Anti-FLIP/CFLAR Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FLIP/CFLAR Antibody |
| 指标别名 | c FLIP;c FLIPL;c FLIPR;c FLIPS;CASH;CASP8AP1;Caspase eight related protein;Caspase homolog;Casper;CFLAR;CFLAR/FLIP;CLARP;FLAME;FLAME 1;FLAME1;FLIP;I FLICE;Inhibitor of FLICE;MRIT;Usurpin |
| 克隆性 | Polyclonal |
| 检验物种 | mouse |
| 应用范围 | ELISA,WB,ICC |
| 基因名称 | CFLAR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | FLIP antibody was raised against a 17 amino acid peptide near the carboxy terminus of mouse FLIP.The immunogen is located within the last 50 amino acids of FLIP. |
| 计算分子量 | 55kDa |
| 成分 | FLIP Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | FLIP Antibody is Antibody is DEAE purified. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain (DD) containing adapter molecules and members of the ICE/CED-3 protease family.Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family.FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP respectively.The human FLIP was also cloned by several labs independently and termed Casper,I-FLICE,FLAME-1,CASH,CLARP and MRIT.FLIP contains two death effector domains (DEDs) and a caspase-like domain.FLIP interacts with adapter protein FADD and caspase-8 and 10,and potently inhibits apoptosis induced by all known death receptors CD95,DR3,TRAIL-R and TNFR1. |
| Uniprot ID | O15519 |
| 基因名全称 | CASP8 and FADD-like apoptosis regulator |
| 蛋白名全称 | CASP8 and FADD-like apoptosis regulator |
| 推荐稀释比 | FLIP antibody can be used for the detection of FLIP by Western blot at 1～2μg/mL.Antibody can also be used for immunocytochemistry starting at 5μg/mL.Antibody validated:Western Blot in human samples and Immunocytochemistry in mouse samples.All other applications and species not yet tested. |
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